Sam Paolini has been a professional artist since dropping out of Massachusetts College of Art in 2008. In March 2010 Paolini founded Wrong Brain, a zine featuring the art and writing of local creatives. Wrong Brain has since expanded to 9 zines, 3 audio compilations, annual alternative art fairs, gallery shows, poetry readings, and other multimedia art events.
From 2010 to 2013, Sam directed the curatorial committee of 30 Under 30, a locally renowned annual art exhibition featuring the Seacoast’s best emerging artists. Paolini has been teaching art at the non-profit art center Main Street Art in Newfields, NH since 2011. In 2012, the children’s book Dream Detectives: Something Funny About the Cake was published, featuring 30 pages of illustrations by Sam. In 2017, Sam traveled across the United States for 77 days, painting murals for free for community centers, nonprofits, communes, and collectives.